If you are using an Apple computer with the latest OS (10.12 Sierra) you may find that plugging in a CH340 chip based Arduinos (used to control the Sienci Mill One) may cause your computer to crash. Luckily there is a driver that makes everything work thanks to Adrian Mihalko.
You can find a link to drivers at https://github.com/adrianmihalko/ch340g-ch34g-ch34x-mac-os-x-driver. I have tried this on my Macbook Air and have been able to connect the CH340 based Arduinos with no issues.
If you are a Windows user, there should be no driver issues. Plug your Arduino in, and if you don’t already have the drivers installed, the computer will auto-download them over your internet connection.